Chinese scientists recently reported that they have developed genetically modified pigs that are immune from the classical swine fever virus (CSFV). Classical swine fever, caused by CSFV, is highly contagious, and the infected pigs often die within a few weeks. CSFV can be transmitted from one pig to another and also from mother to offspring. Both domestic and wild pigs can get infected with the virus…Full Article: Xinhua Dec 2018

Key Point

  • Scientists within Jilin University’s College of Animal Sciences developed transgenic CSF-resistant pigs by utilizing the CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 gene-editing tool with the RNA interference (RNAi) technique.

ChinaAg Comments

  • Classical swine fever (CSF or hog cholera) and African swine fever (ASF) are highly virulent pig diseases that share near identical symptoms and death rates. As a result, laboratory tests are needed to distinguish between the two. In general, ASF is genetically “more complex” and is caused by a unrelated DNA virus when compared to CSF.
  • In 1954, China developed the lapinized attenuated vaccine C-strain for vaccination against Classical swine fever virus (CSFV) in pigs.

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